(S,R,S)-AHPC-Me hydrochloride

(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader.


Cat. No.: EX-A3957	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1g	485	In-stock
2g	785	In-stock
5g	1185	In-stock
25g	1885	In-stock
100g	get quote	In-stock

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


Synonyms	VHL ligand 2 hydrochloride
Synonyms 2	E3 ligase Ligand 1
CAS No.	1948273-03-7
Purity	>98%
Formula	C23H33ClN4O3S
Mol Weight	481.051
Appearance	solid powder
Solubility	Soluble in DMSO and water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. WO/2017/030814A1 [2]. Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9.
CoA	CoA of (S,R,S)-AHPC-Me hydrochloride

Smiles:	N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O.Cl


		Search